Below you can find the This isthmus was explored by columbus in 1502 & crossed by balboa in september 1513 Jeopardy Words Answer. The answer to This isthmus was explored by columbus in 1502 & crossed by balboa in september 1513 has 6 letters. This clue belongs to the All i want for isthmus category and is part of Jeopardy Word Level 297. If you scroll near the bottom you will find other clues and answers part of level 297